Chronic Pain

Conveniently located to serve the areas of San Clemente and Orange County, CA

Chronic Pain Treatment

Welcome to our page dedicated to Osteoarthritis & Chronic Pain. Here you will find a wide range of education and experiences pertaining to these conditions. We look forward to helping you gain the education and awareness you need to make the most informed decision on the next steps.


This is Natalie. Having been frustrated by not getting what she needed from her previous medical providers and needing to be able to work she decided to come to Dr.Steenblock and the Personalized Regenerative Medicine team to address the pain and restriction she was having from her previous knee replacement.

With the use of stem cells, she showed immediate results and now without the restrictions she once had, she is able to work and live with the quality of life that she desires. This video captures her candidly sharing her experience at Personalized Regenerative Medicine.

About Chronic Pain Diagnosis

When a doctor sees a patient for the first time he will ask for copies of medical records as part of gathering information and data that, in combination with taking a medical history and doing relevant exams and tests, help him arrive at diagnosis (or confirm those previously made) and formulate a medical care plan. Dr. Steenblock does all this, yes, but goes beyond this. How so? He ferrets out the previously undetected cause(s) and contributors to a person’s problems. This medical sleuthing or Sherlock Holmes mindset is what helps Dr. Steenblock come up with answers in situations where others have failed. Not surprisingly his track record of “discerning what has escaped other docs” has earned him the moniker “Doctor’s doctor” by his patients and a great many of his colleagues. How did Dr. Steenblock come to be a “medical sleuth”?

Medical Sleuthing

Dr. Steenblock spent years working in pathology, the science of studying and diagnosing disease.

Medical sleuths are not born but made. The truly good ones have agile minds, intense curiosity, critical thinking skills, and sound medical and scientific education. Dr. Steenblock certainly has all this and more. His native abilities are reflected in a lifetime of accomplishments including spinning new ideas and inventions. His education and training are a matter of public record: A B.S. degree from Iowa State University in zoology, an M.S. in Biochemistry and Doctor of Osteopathy degree from the College of Osteopathic Medicine and Surgery in Des Moines, Iowa, followed by post-doctoral training that included three years at Case Western Reserve University, one year at the Oregon Health Sciences University and a clinical Rotating Internship at Providence Hospital in Seattle, Washington. Also — and very integral to doing medical detective work

Estimates vary but it appears around 4% of medical diagnoses are just plain wrong. Dr. Steenblock has run across this many times during his forty-four years of medical practice (40,000+ patients). Some of these patients had “consensus diagnoses” (a medical diagnosis made by 2 or more doctors) that turned out to be dead wrong. Needless to say, getting properly diagnosed helped get these folks on the right road. This is something Dr. Steenblock has in-mind with each and every patient who comes in to see him. Dr. David Steenblock and Personalized Regenerative Medicine’s mission is to deliver advanced care for chronic and degenerative diseases.

Pain Testing and Assessments

One of the central planks in Dr. David Steenblock’s practice of personalized medicine is to cover all the testing and diagnostic bases. The first step in this process is typically to do a complete physical examination, including routine lab work and any specialized testing Dr. Steenblock deems essential.

Bone Marrow

Given the fact that each person’s bone marrow stem cells play a crucial role in healing damaged or diseased organs and tissues, Dr. Steenblock also tests for things that interfere with stem cell mobilization as well as their vitality and activity. This includes testing to determine the presence and levels of heavy metals such as mercury, lead, cadmium, arsenic, etc. For adults, this is done using Dimercaptosuccinic acid (DMSA), which is an oral chelating agent that binds to heavy metals.  A one-time dose of DMSA is taken by the patient, followed by 6 hours of urine collection.  A sample is then sent to Doctor’s Data in Chicago for analysis.

Hormone Deficiency

Hormone deficiencies and excesses (e.g. hyperthyroidism, hypothyroidism, etc.) can impact stem cells, as well as the tissues into which they engraft.  This hormonal imbalance can bring about cellular changes that can dampen or otherwise impede stem cell activity. Dr. Steenblock prescribes hormone panel tests that measure such hormones as DHEA, IGF-1HGH, estrogen, progesterone, and testosterone and prolactin.


Physical stressors including, but not limited to hypoxia (low blood and tissue oxygen levels), intermittent hypoxia, nocturnal hypoxemia (serious drops in tissue oxygen levels during sleep), chronic persistent hypoxia secondary to COPD (emphysema), metabolic acidosis (happens in poorly controlled diabetes) or other noxious tissue conditions are also deterrents for stem cell activity. To detect & measure the extent of these Dr. Steenblock runs tests that measure carbon dioxide (CO2) blood levels, LDH isoenzymes & lactic acidpyruvic acid levels, salivary, and urine pH. In addition, Dr. Steenblock may also order a nocturnal oximetry test, electrocardiogram (EKG), and pulmonary function studies.


These sorts of infections tend to attract stem cells, including those that would ordinarily wind up supporting the body’s own repair and restoration processes.

Dr. Steenblock looks for active infections whether bacterial, viral, or mycoplasma in nature in gums, sinuses, organs, or other tissues, plus smoldering or hard-to-detect low-grade infections, especially those caused by certain herpes viruses and retroviruses. Tests that Dr. Steenblock may utilize, when indicated, include a computed tomography (CT) scan of the lungs and sinuses to rule out sinus infections and a Comprehensive Digestive Stool Analysis (CDSA) plus Parasite test to rule out intestinal issues, including disturbances in bowel ecology.


Poor nutrition, consumption of unhealthy fats and simple sugars, binge or heavy drinking, consumption of carbonated beverages (especially those that are sugar-laden), overconsumption of caffeine, and so on, can make many medical conditions worse. In addition, lack of certain nutrients, like vitamin D, as well as excess amounts of others, such as vitamins K and A, can all impede or interfere with the viability & activity of stem cells. Generally, Dr. Steenblock conducts a systematic review of a patient’s diet, which may require the patient to keep a food diary for a period of time.  In addition, specialized testing may be done to more accurately determine the patient’s nutritional needs.

Medication and Supplements

Drug interactions and excessive or wrong drug choices, including herbal supplements, vitamins, and minerals can potentially create medical problems or complicate and negatively impact various diseases and conditions, not to mention adversely affecting stem cell growth, proliferation or function. Therefore, Dr. Steenblock typically reviews each patient’s past & present prescription and over-the-counter (OTC) pharmaceuticals, herbs, herbal teas and supplements, vitamins and minerals, as well as illicit drugs in order to be able to make the safest and most effective decisions for the patient’s regenerative health.

Dr. Steenblock makes use of various highly sophisticated tests to help gauge such things as how a patient is likely to respond to a particular ordered medication or ascertaining a patient’s risk of developing certain types of chronic diseases in the future. One comprehensive genetics test Dr. Steenblock often orders for his patients is 23andme. This kind of testing makes it possible for him to individualize many aspects of the care he provides.

Lab Tests

In addition to the aforementioned tests, Dr. Steenblock may also order some or all of the following labs to help complete his assessment and develop a more personalized treatment plan:   Complete Blood Count (CBC)Erythrocyte Sedimentation Rate (ESR), C-Reactive Protein (CRP), thyroid paneluric acidammonia (brain cases), erythropoietin (EPO) test if anemia is present, reticulocyte count, iron, Total iron-binding capacity test (TIBC)oxygen % saturation, copper, ceruloplasmin,  Antinuclear Antibody Test with reflex, and urine organic acids.

Your Personalized Treatment Plan

Charting Your Personal Course

Once a patient’s diagnosis is confirmed, modified, or even overturned and the results of all tests ordered are in, Dr. Steenblock can then put all the pieces together to create a personalized treatment plan. This simply means that therapies and treatments are matched to the individual and their unique biochemical and genetic make-up, as well as other characteristics and features, including those of their particular medical challenges. This process helps increase the patient’s potential for optimal outcomes and significant clinical improvements.

Treatment Strategies Can Include

  • Addressing heavy metal toxicity using chelation therapy
  • Balancing hormone levels through hormone replacement therapy
  • Treating various infections using antimicrobial therapies
  • Addressing nutritional deficiencies and unique dietary needs through individualized therapeutic diet plans, oral supplements, and IV nutritional therapies
  • Prescribing or changing pharmaceutical medications and nutritional supplements in order to maximize their benefits for health and regenerative capacity, as well as minimize any potential adverse reactions or interactions

Additional Treatment Modalities

  • Hyperbaric oxygen therapy (HBOT)
  • Periodic acceleration therapy (PAT)
  • Pulsed magnetic field therapy (PMFT)
  • Hyperthermia
  • External counterpulsation
  • Hyperthermic Ozone and Carbonic Acid Transdermal Therapy (HOCATT)
  • IV or Oral Chelation
  • Nutritional or Other Intravenous Therapies
  • Platelet Rich Plasma Therapy
  • Stem Cell Therapies

Health Challenges We Treat