Acute and Chronic

StrokeDuring the past twenty years Dr. David Steenblock has treated over 2000 stroke patients using daily hyperbaric oxygen and other modalities. As-a-result he has learned a great deal about what it takes to help stroke patients get their best shot at improvement. In addition and perhaps most exciting of all is the fact Dr. Steenblock and his medical team has been closely studying the use of various types of stem cells with patients suffering from the after-effects of stroke.  One way they have done this is to track patients treated with umbilical cord stem cells in Mexico (Some of this work is being done by Dr. David Steenblock’s namesake nonprofit research institute, Steenblock Research Institute.) Another is experiential; that is, Dr. Steenblock has taken stem cell-rich bone marrow and fat and used a different number of ways to give these to chronic stroke patients. The simplest method he has used is to give these tissues by intravenous (IV) drip. He has found that this works best in patients who are 2-3 weeks or less out from their stroke. Dr. David Steenblock notes that “This is a good method since the blood brain barrier is still damaged and open which makes it easy for stem cells to migrate into damaged areas of the brain.”

As you might expect the brain begins to heal the disrupted blood-brain-barrier with the passage of time which makes it increasingly hard for stem cells to migrate through to reach damaged tissues. Dr. Steenblock has found that the younger and more vigorous the stem cells are, the greater the penetration and the better the clinical results. Given this it is not surprising that he advocates that patients who can afford to do so got to Mexico and have their “brain flooded with umbilical cord stem cells”. However, once a patient’s post-stroke period stretches beyond 3-4 weeks the use of other methods is needed in order to get the stem cells where they will do the most good. One of these methods is the intravenous use of the FDA approved drug mannitol at least one hour prior to giving the stem cells. Mannitol is a simple sugar that opens the blood-brain-barrier and keeps it open for a few hours afterwards.  Following administration of mannitol Dr. Steenblock infuses stem cell-rich tissue either intravenously or preferably intra-arterially.

Another method which avoids all of this is the use of pure stem cells isolated from a patient’s bone marrow or fat that is infused into the cerebrospinal fluid by way of an intrathecal or lumbar puncture procedure.  During such a treatment 50 million stem cells are injected into the cerebrospinal fluid using a simple procedure. This treatment is ideally repeated weekly or as desired to get as many stem cells into the damaged brain as possible (The only limitation is a patient’s availability.) As isolating and culturing stem cells is not permitted in the US outside of approved clinical studies, this kind of treatment is done in Mexico.

Stroke Treatment with Dr. David Steenblock

Let’s look at what would be the likely treatment scenario for a patient who can spend one month with Dr. Steenblock:

Initially, he would be given his own stem cell-rich bone marrow and/or fat tissue intravenously. Some of these cells would be taken to a Mexican hematology lab and cultured. Two weeks later the patient would be transported to Tijuana and begin receiving weekly or bi-weekly cerebrospinal stem cell infusion treatments. Once in the CSF the cells will circulate through the brain and its damaged portions.

For patients who can stay two months at least six injections of pure stem cells would be given directly into the cerebrospinal fluid.

Whether a patient has treatments in the US or Mexico or both, the main point to keep in mind is this: Dr. Steenblock has the knowledge and experience to design a program for stroke patients that will insure that millions of stem cells wind up in their damaged brain.  A typical program includes: (1) Daily injections of FDA approved stem cell mobilizing drugs; (2) Daily Hyperbaric Oxygen  which mobilizes stem cells; (3) Daily use of External counterpulsation or the periodic acceleration bed, both of which stimulates blood vessels to make VEGF (Vascular Endothelial Growth Factor) which gets stem cells to make new blood vessels in the damaged parts of a patient’s brain; (4) Daily supplements to help stem cells grow and repair the brain; and (5) Daily growth factors to help stem cells repair the damaged areas of the patient’s brain.

Support for using Hyperbaric Oxygen Therapy to Treat Stroke

Dr. Steenblock’s Clinic Study – Stroke Patient Responses (50 patients treated with HBOT, Physical Therapy & Biofeedback)


Support for using stem cells for acute & chronic stroke

Bone Marrow Stromal Stem Cells May Aid in Stroke Recovery (Science Daily December 1, 2010)

A research study from the Farber Institute for Neurosciences and the Department of Neuroscience at Thomas Jefferson University determines bone marrow stromal stem cells may aid in stroke recovery. The results can be found in Cell Transplantation — The Regenerative Medicine Journal.

The study examining the effects of a systematic administration of either rat (allogenic) or human (xenogenic) bone marrow stem cells (MSC) administered to laboratory rats one day after their simulated strokes found “significant recovery” of motor behavior on the first day. Early administration was found to be more effective than administration seven days after the simulated strokes.

  • Advantages of human cord blood cells in CNS injuries and disorders
  • Greater long term improvement with intravenous delivery to the femoral vein
  • Cord blood cells improve recovery in rat models for stroke

Umbilical Cord Stem Cells and Stroke Treatment (Steenblock Research Institute)

ASA: Fat Stem Cells Repair Stroke Damage in Rats

Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats

Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy. Ikegame Y, Yamashita K, Hayashi S, Mizuno H, Tawada M, You F, Yamada K, Tanaka Y, Egashira Y, Nakashima S, Yoshimura S, Iwama T. Cytotherapy. 2011 Jul;13(6):675-85. Epub 2011 Jan 13.

Functional recovery after hematic administration of allogenic mesenchymal stem cells in acute ischemic stroke in rats. Gutiérrez-Fernández M, Rodríguez-Frutos B, Alvarez-Grech J, Vallejo-Cremades MT, Expósito-Alcaide M, Merino J, Roda JM, Díez-Tejedor E. Neuroscience. 2011 Feb 23;175:394-405. Epub 2010 Dec 7.


Intravenous Stem Cells after Ischemic Stroke (ISIS) – Clinical study recruiting

Autologous Bone Marrow Stem Cells in Middle Cerebral Artery Acute Stroke Treatment – Clinical study recruiting


PATIENT VIDEOS (Dr. Steenblock’s Clinic):

Joe Beschen tells his story of coming back for a major stroke thanks to Dr. Steenblock and HBOT, etc.


The Dale Hartley Story: A Stroke Ten Years Ago “I’m Still Here”

Dale Hartley suffered a stroke ten and a half years ago. Dale had heard about Dr. Steenblock’s program on the radio. He was as thrilled then as today that Dr. Steenblock had something more to offer than conventional medicine. He and his wife Audrey came to Dr. Steenblock’s clinic to undergo the stroke program. When Dale arrived at the clinic he began the full program of chelation and hyperbaric oxygen therapy, and as he tells it, “my sister had a stroke three years after me; she didn’t come to Dr. Steenblock. Unfortunately, she’s gone- I’m still here.”

Like many who suffer a massive stroke, with such an insult to the brain, to just “still be here” is a miracle in itself. But Dale and his wife Audrey wanted more. They did their research and concluded they wanted to try umbilical cord stem cells in Mexico.

About two and a half years ago Dale had umbilical cord stem cells. He believes they made him stronger.

Then recently, he and Audrey learned about Dr. Steenblock’s Personalized Regenerative Medicine and the use of your own bone marrow stem cells. They excitedly packed up their precious little Bianca, and made the drive down from Malibu (where they live) to have this procedure done. Audrey had it done as well.

With a big bright smile, Dale will tell you that after having the bone marrow stem cells the first time his eyesight improved, and both of his knees (which hadn’t been “working” he said), were back to “almost normal”. In addition, his hip joint was back to normal, and he believes he has better balance when walking.

Audrey says that her knee problems (the meniscus) were getting signs of arthritis, and she also wanted to make sure she didn’t lose the strength of her grip to arthritis. She has noticed after her bone marrow stem cells that her constant sinus drip was nearly gone.

Both Dale and Audrey did bone marrow stem cells twice, six weeks apart. Both report a resounding success, and when asked if they’d do it again, they’ll tell you, “Absolutely!”


If you are interested in learning more about this treatment approach you can get a consultation with Dr. Steenblock by calling 1-800-300-1063 or by e-mailing

Also: Please visit Dr. Steenblock’s website dedicated to helping restore patients who have suffered from a stroke or TIA.